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There, the pleiotropic beneficial effect, along with cytoprotection concept implementation, regulation of the increasing angiogenesis, increased VEGF, increased egr-1 gene, increased NO, or eNOS stimulation, and counteraction of the increased free radical formation, occur through a network of closely interconnected pathways presented in this review (see Section 1, Section 2 and Section 3)
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168,169 Notably, the FMRP-eIF4E-CYFIP1 complex regulates the translation of more than 1000 genes, many of which are ASD risk genes
Mechanistic and gene-expression human data
A: Some studies suggest activity when administered orally or via injection in animal models, but this is still under investigation and not clinically validated