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Provides Cell-Protective Effect By lowering oxidative stress, glutathione helps protect: Nerves Kidneys Eyes Blood vessels Helps Reduce Diabetic Complications Oxidative stress is linked to: Neuropathy Retinopathy Kidney damage In studies, glutathione has shown protective effects against these complications

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Notably, breast cancer cells achieve metabolic adaptation by hijacking the autophagy mechanism: under glucose-deprivation conditions, MANF-mediated mitophagy eliminates dysfunctional mitochondria through the PRKN/Parkin-dependent pathway, maintains the ATP supply and promotes tumour survival [112], suggesting that targeting the MANFPRKN interaction can break the drug resistance barrier of breast cancer under metabolic stress

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