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Disruption of the ECM predictably impairs the structural integrity of the BBB, which in turn compromises its activity

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To minimize non-specific binding, 5% BSA was used for blocking

The results indicate that FOXO4-DRI potently and selectively reduces the viability of senescent fibroblasts compared to non-senescent controls (2.7-fold and 1.7-fold difference for keloid and normal skin, respectively)

[DOI] [PubMed] [Google Scholar] Keith DE, Murray SR, Zaki PA, Chu PC, Lissin DV, Kang L, et al

SIBO is characterised by an abnormal increase in bacteria (typically gram-negative organisms from the colon) in the small intestine