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Supplementary information Rights and permissions About this article Cite this article Muttenthaler, M., King, G.F., Adams, D.J
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These findings open the opportunities for therapy targeting metabolic cross talk between cancer cells and cancer-associated fibroblasts [159]
In mice, a total of 24 selenoproteins have been characterized 46 and targeted deletion of some of these selenoproteins demonstrated their essential roles in developmental processes and in disease pathogenesis
Effects of an effective concentration of nicotine (N 250 g/ml) in the presence or absence of glutathione (G 14 g/ml) on the metabolism of 14C-testosterone and 14C-4-androstenedione in HGF (Figures 3 & 4) When 14C-testosterone was used as substrate (Figure 3) there was a 2-fold reduction in the production of D (a metabolite of DHT) when compared to controls in response to N with 33% less inhibition when G was added (NG 2,3,4 )
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