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This mismatch between iron intake and storage capacity creates a physiological vulnerability: while robust iron uptake supports accelerated hematopoiesis and tissue expansion necessary for normal growth, it simultaneously increases childrens vulnerability to pathogen-driven iron dysregulation and the subsequent activation of ferroptosis pathways

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Results Sulforaphane ameliorated rotenone-induced motor function deficits in mice Sulforaphane did not show any toxicity in our study and has been used previously as a protective reagent at a dose of 50 mg/kg in vivo 27,37,38

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It is also worth noting that glutathione levels decline with age, starting from around the age of 50