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For example, IGF-IR and ErbB3 were significantly upregulated in ovarian cancer cells resistant to the anti-ErbB2 mAb trastuzumab [116]

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However, in genetically predisposed individuals, a subset of autoreactive T cells can evade these mechanisms, become activated, proliferate, and differentiate, initiating an autoimmune cascade (Fig

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Examples of oxidation are when an apple starts turning brown after it is cut or rust accumulating on a something made from iron, like the body of a car