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, Increased consumption of NADPH may also impair glutathione reductase activity

Despite preventing steatosis, SCD1 knockout exacerbated hepatic fibrosis and cellular apoptosis in mice with NASH induced by a methionine and choline deficient diet [61]

Mitochondrial dysfunction amplifies reactive oxygen species (ROS) production, inducing DNA damage and hyperactivating PARP-1 [105]

Multi-omics analysis reveals mechanisms of FMT in enhancing antidepressant effects of SSRIs

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