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Hormonal status: Perimenopausal and postmenopausal women may see a slower response due to estrogen-driven collagen decline

The Grx1 domain equilibrates rapidly with the local GSH/GSSG pool, transferring the redox information to roGFP2

This was subsequently shown to be associated with lower levels of heme-artemisinin adducts 21 and reduced fluorescence labelling of proteins using an artemisinin-based activity probe 12

Pyridoxine/pyridoxamine 5-phosphate oxidase (Sgll/PNPO) is important for DNA integrity and glucose homeostasis maintenance in Drosophila