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However, because MOTS-c affects glucose metabolism, patients on diabetes medications require careful monitoring and potential dose adjustments during the protocol

Because SAAR removes cysteine from the diet, the authors wanted to determine whether cysteine restriction was responsible not only for the anti-obesity effects, but also for bone-related side effects

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It has also been reported to ameliorate the effects of reactive oxygen species (ROS) and free radical-induced oxidative stress (OS) and minimizing pathological disorders of sperm, like adenosine triphosphate (ATP) depletion leading to insufficient axonemal phosphorylation, lipid peroxidation as well as loss of motility and viability [9, 10]

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