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If you do need to raise the dose, only do it by 1/2 unit

The primary endpoints that track response to MOTS-c therapy align with the peptide's core mechanisms: insulin sensitivity, mitochondrial function, body composition, and inflammatory tone

Studied in models involving neurotrophic pathway behavior, neuronal signaling systems, CNS peptide biology, and cellular response pathways

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doi: 10.1034/j.1399-3003.1999.14d02.x