Disturbances of this metabolic interaction between astrocytes and neurons will affect GSH homeostasis in brain and could contribute to a compromised antioxidative defense in neurological diseases
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Despite widespread adoption, these agents are not approved by the U.S
The IL-6 cytokine and its receptor have garnered significant attention as important therapeutic targets [101, 102]
BH3 peptides/mimetics in DTEP buffer (300 mM trehalose, 10 mM HEPES-KOH, 0.1% w/v BSA, 1 mM EDTA, 1 mM EGTA, 80 mM KCl, 5 mM succinate, final pH 7.4) were plated at 70 M l 1 (unless otherwise stated) in triplicate in a black 384-well plate
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