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doi: 10.1080/07388551.2016.1260525 32 AbeciaJAMeikleAVzquezMICasaoAForcadaFSosaC

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Recent studies of peptide-bound, active, Gs-coupled, structures of CTR or AMYRs provide evidence supporting distinct conformations of receptors when bound to CT peptides versus amylin peptides 15 that may contribute to pharmacological differences between dual CTR and AMYR agonists

[7] The preclinical work is more mechanistically detailed but is animal and in-vitro data, which never translates one-to-one to human dosing

The localized mechanism explains the result: BPC-157 activates the fibroblasts that produce tendon collagen directly at the repair site