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[PMC free article: PMC6646716] [PubMed: 31379733] 81

Denatured peptide molecules lose their biological activity

The committee's vote is advisory

stiffness and resistance to limb movement caused by increased muscle tone and/or an excessive and continuous contraction of muscles, which may be uniform (lead-pipe rigidity) or ratchety (cogwheel rigidity), and which may be associated with joint pain

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AOD-9604, thanks to its mechanism (lipolysis directly from adipose tissue without effect on muscle cells), may help steer the weight reduction toward the fat component