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In some embodiments, the excipients, carriers, adjuvants, are useful in forming a pharmaceutically acceptable formulation or composition
Prolonged inflammation results in damage to the GI tract
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For example, copper ions can lead to GSH depletion through two mechanisms: the direct downregulation via the redox reaction between Cu 2+ and intracellular GSH, and the activation of a Fenton-like reaction by generating Cu + to amplify oxidative stress (Dong et al., 2020)
Abstract The transsulfuration (TSS) pathway is an alternative source of cysteine for glutathione synthesis