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Although there are no studies that have specifically examined the effects of CGRP on muc5AC or muc5B expression in COPD, finding altered CGRP receptor expression in COPD airway epithelial cells suggests a possible influence of CGRP on muc5AC and muc5B expression

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CALLENDER V

Effect of N-acetylcysteine on exacerbations of bronchiectasis (BENE): a randomized controlled trial

(E) TMAO production induces NLRP3 inflammasome and caspase-1 activity leading to increased inflammation

Phase II clinical trials for inflammatory bowel disease reported no toxicity or adverse events in treated patients, though detailed safety data from these trials have not been published in peer-reviewed literature