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Zhang, Y., Zhang, H., Ghosh, D., & Williams, R

After Bayer discontinued its Climara estradiol patch in late 2023, the U.S

Some peptides are studied in injectable form, while others are explored in alternative formats depending on the protocol

This Research Topic aims to highlight recent advancements and challenges in MS-based adductomics within biological matrices, and further adductomic approaches to the study of the exposome in health and disease

For example, a bile acid metabolite (gut microbiome-derived glycochenodeoxycholic acid) activates the TFR/ACSL4 pathway to induce ferroptosis, promoting progression of environmental toxin-associated metabolic dysfunction-associated fatty liver disease (Liu et al., 2022a)

The scoring criteria focused on key morphological indicators of kidney injury following ischemia-reperfusion, including loss of the brush border, tubular dilation, degeneration, necrosis, and the presence of tubular casts