Although the evidence is minimal for the influence of GST polymorphisms of the alpha, mu, pi, and theta classes on susceptibility to various types of cancer, numerous studies have implicated such genotypic variations in asthma, atherosclerosis, allergies, and other inflammatory diseases
PubMed Central, doi:10.1016/j.envint.2017.12.014
In particular, experiments with the inhibitor of GSH1 buthionine sulfoximine have helped to demonstrate the existence of an active catabolism of glutathione
2.11 Western blotting CLL cells were lysed in a radio-immunoprecipitation assay buffer (Millipore-Sigma) with cOmplete mini protease inhibitor tablets (Roche) and were processed to extract the total protein
American Journal of Human Genetics
Hewitt, N