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Ubillos L, Freire T, Berriel E, Chiribao ML, Chiale C, Festari MF, et al

The secretion of GHRH is stimulated by several factors including depolarization, 2-adrenergic stimulation, hypophysectomy, thyroidectomy, and hypoglycemia and it is inhibited by somatostatin, IGF-I, and activation of GABAergic neurons

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In controlled laboratory studies utilizing UV-damaged tissue models, GHK-Cu administration reduced inflammatory markers by 35% while simultaneously increasing the expression of tissue repair genes