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It resists degradation in the acidic environment of the stomach and maintains biological activity across a range of conditions

Acta 1545 , 6777 (2001)

You're currently receiving medication or treatments that affect bone marrow

We were exploring ways of developing peptides that bind selectively, and we were very successful at that, but then we confronted the problem that our short, 23-residue peptides are not promising therapeutic candidates primarily because they cannot get into cells, Keating says

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Chemotherapy with drugs like 5-fluorouracil has also been associated with acute thiamine deficiency by disrupting thiamine activation, so oncology patients receiving such therapy might receive parenteral thiamine supplementation as part of this B-Complex if needed