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Vitamin B 6 was included in the medication Bendectin (a delayed-release formulation of 10 mg doxylamine succinate [an antihistamine] and 10 mg pyridoxine hydrochloride [vitamin B 6 ]), which was prescribed for the treatment of morning sickness and later withdrawn from the market in 1983 due to unproven concerns that it increased the risk of birth defects (80)

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Since decreased Parasutterella relative abundance may accompany increased stress 80,81 , the increased Parasutterella relative abundance that occurred in this study following diet switch likely arose from the weight loss-mediated negative energy state