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133 Another randomized controlled trial in 57 subjects undergoing evaluation for male infertility found taking an oil providing 990 mg DHA and 135 mg EPA daily for 10 weeks decreased sperm DNA fragmentation and increased seminal antioxidant status more than a sunflower oil placebo, but did not affect other sperm parameters

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However, its half-life in the bloodstream is remarkably short, around 15 minutes, due to rapid degradation by aminopeptidase enzymes

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Less common, whole-body effects