According to the guidelines of the International Pediatric Sepsis Consensus Conference 104 , neonatal sepsis is defined as a clinical syndrome characterized by the presence of both infection and systemic inflammatory response syndrome (SIRS) and can cause severe neurological complications due to brain infection, as well as secondary hypoxemia resulting from septic shock, pulmonary hypertension and severe lung disease
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Moreover, numerous studies found that individuals with severe illnesses, such as sepsis, had decreased plasma vitamin C concentrations, they also revealed a connection between this decline and the beginning of multiple organ failure [42,43,44,45]
These factors can lead to fluctuations in Hcy levels, potentially affecting its accuracy as a predictive marker for diabetic complications
doi:10.1016/j.femsyr.2005.06.001 Elskens MT, Jaspers CJ, Penninckx MJ (1991) Glutathione as an endogenous sulphur source in the yeast Saccharomyces cerevisiae
