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Delta sleep-inducing peptide (DSIP) is composed of 9 amino acids and has been implicated in the regulation of sleep, modulation of stress ( Pichia pastoris , emerges as a promising candidate in this regard, with its sedative and hypnotic effects garnering significant interest
This insight comes from in vitro studies, which means studies done on cells isolated outside of the body (imagine scientists looking under a microscope at a petri dish)
10.1038/nchembio.109
it also contains glutathione
In some embodiments, the otic formulation or composition comprises between about 0.001% to about 1% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof