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If so, NET-directed diagnostics (e.g., circulating MPODNA or citrullinated histone H3) and targeted interventions (DNase, PAD4 inhibitors, anti-platelet strategies that disrupt plateletneutrophil conjugation) could represent novel approaches to mitigate CV risk in PCOSan avenue that urgently warrants prospective, mechanism-focused clinical investigation (see Fig

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Its works like a biological clock, when it secretes the melatonin at night, united to other neuropeptides (Maffei, 1978)

Since palpitations are often intermittent, a normal ECG does not rule out an episodic rhythm problem

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