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Due to neurons having a limited capacity for GSH synthesis, they must rely on astrocytes to supply precursors such as cysteine (Prez-Sala D and Pajares, 2023)

This is because hemoglobin A1C (a measure of blood sugar control) and sex hormone-binding globulin (SHBG) are inversely correlated: as A1C improves with weight loss, SHBG levels may rise, which can bind more testosterone and reduce the amount that circulates freely in the bloodstream

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Anti-Doping Agency (USADA) Mechanistic claims (angiogenesis modulation, nitric oxide pathway, cytoprotection) are preclinical

It has been reported that cystine starvation alone was sufficient to induce ferroptosis in mouse embryonic fibroblasts, which was associated with an outburst of ROS 31