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doi: 10.1046/j.13652826.2000.00456.x 52 KahODubourgPOntenienteBGeffardMCalasA

In models of traumatic brain injury, AQP4 depolarization impedes tau clearance, and global Aqp4 knockout worsens neuropathology [412]

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This increases susceptibility derives from an impaired mucus secretion from goblet cells in NLRP6-deficient mice, determining a reduced mucus layer [29]