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10.1038/s41467-021-21804-1 87

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This systematic review of studies published over the last decade aimed to comprehensively evaluate the safety and efficacy of CA for the management of AWE

Chronic benfotiamine administration was also shown to decrease the number of neurofibrillary tangles in certain brain regions and improve survival in a mouse model (63)

Scientifically, that line leans more into metabolic efficiency and blood-flow support