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The first cardiovascular study of NNMT enzyme inhibition in a heart failure with preserved ejection fraction (HFpEF) mouse model demonstrated that treatment markedly reduced 1-MNA (by 77.1%), 2PY (by 66.2%), and 4PY (by 71.1%) in cardiac tissue, while improving cardiac function, enhancing global longitudinal strain, reversing peak longitudinal strain rate, and significantly reducing left ventricular hypertrophy and fibrosis

AOD9604, a growth hormone fragment, prevents weight gain and reduces body fat in obese animals

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The peptide itself is prepared by a licensed compounding pharmacy, since the original FDA-approved drug is no longer manufactured or sold

Researchers have documented few side effects