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doi: 10.1111/j.1600-079X.2008.00555.x 73 SatiL

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HSCs, the primary producers of ECM, play an indispensable role in the pathogenesis of liver fibrosis ( The pathogenesis of liver fibrosis is complex, with sustained HSC activation and ECM deposition due to chronic liver injury being major contributors ( in vitro and animal models has revealed multiple pathways by which glycyrrhizin inhibits HSC activation

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We also proposed potential biological mechanisms, such as glial cells (microglia astrocytes), autophagy, and apoptosis

Endocrinol Diabetes Metab Case Rep 2021:210070