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They're probably investing something like $100,000 into these before they're even fully out yet, he says

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This points to the fact that study designs capturing only the post-acute phase may not take into account valuable explanations for pathogenesis of PASC (132)

This ineffective clearance, combined with generally poor hepatic function, may result in chronic encephalopathy, punctuated by acute exacerbations often precipitated by gastrointestinal bleeding from esophageal varices (resulting in an increased intestinal ammonia load), infection, excessive protein intake, or overzealous diuresis to treat ascites

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