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It's not unusual for the symptoms of B12 deficiency to get worse when treatment starts - part of the repair effect - and irritability / mood issues are know symptoms of B12 deficiency, so this may explain your reaction to the B12 shots

Continue Reading How quickly do B12 shots work

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This makes it particularly valuable for identifying ligament injury and guiding both diagnostic and therapeutic injections

One option is vitamin B12, which can prove particularly potent when administered via injection