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TB-500 Synonyms / Designations: TB-500, Thymosin Beta-4 Fragment, Synthetic Thymosin b4Derived Peptide CAS Number: 77591-33-4 Molecular Formula: C212H350N56O78S Molecular Weight: ~4963.0 g/mol Peptide Length: 43 amino acids Peptide Type: Synthetic peptide derived from thymosin beta-4 Purity: 99 % (HPLC, typical) Appearance: White to off-white lyophilised powder Pack Size: 5 mg (typical) Storage: Desiccated, protected from light, stored at 20 C or below Solubility: Soluble in water and buffered aqueous solutions Description & Mechanism TB-500 is a synthetic peptide derived from the active region of thymosin beta-4, developed for experimental investigation of actin-binding dynamics, cell migration, and cytoskeletal organisation in controlled research settings

One primary issue is the presence of conserved binding sites across different GST isoforms, which increases the risk of off-target effects

W., Freund, G

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doi:10.1089/omi.2014.0018

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