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Glucose transporters are in a continuous state of turnover

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Key parameters include fasting glucose, HbA1c, liver enzymes (ALT, AST), lipid panel, and body composition metrics

During this second cycle, 2 NP was removed again through the action of the activated MsrA and MsrB expression in the engineered bacteria

It has been proposed that ATXN3 is also degraded through autophagy [83], being the mutant (soluble) protein more prone to autophagic degradation, as no changes in endogenous wild-type ATXN3 levels were observed in drug-induced autophagy activation in vivo [84]

Sci 342(6163):12031208