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Treatment Approach: XERF Lifting 1 Dual-Frequency RF Energy (6.78MHz + 2MHz) Unlike traditional single-frequency RF devices, XERF simultaneously uses two distinct frequencies 6.78MHz and 2MHz to more precisely target both superficial and deeper skin layers

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We defined two sets of genes, those either largely devoid of promoter bound NRF2 (Group I, green) or genes with high promoter bound NRF2 (Group II, purple) (Fig

doi: 10.1155/2013/424163 202 PaparoSRFerrariSMPatrizioAEliaGRagusaFBotriniCet al

2012;23(8):1187 to 1208

Fish JE, Yan MS, Matouk CC, St Bernard R, Ho JJ, Gavryushova A, Srivastava D, Marsden PA (2010) Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones