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Until then, the most accurate answer is: Retatrutide is the higher-upside candidate, while CagriSema is the more incremental combination strategy

We dont know yet

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More specifically, the researchers investigated the potential of the peptide in pancreatic islet transplantation (PITx) models, which typically demonstrates limited success due to islet damage that occurs during isolation and from the severe inflammatory reactions caused by the transplantation procedure

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It can also be a trigger for many conditions of autoimmunity