Signs of healthy barrier: Skin feels comfortable Minimal sensitivity to products Consistent texture Appropriate oil production (not too dry, not too oily) Signs of compromised barrier: Stinging with products that normally don't sting Increased sensitivity Redness Flaking or unusual dryness More reactive to environmental factors If barrier is compromised: Stop copper peptides until repaired Focus on gentle cleansing, moisturizing, protecting Takes 2-6 weeks to repair depending on severity Rule 3: Apply to clean, dry skin Wet skin has temporarily compromised barrier (swelling of stratum corneum)
BBB parameters improved to the levels close to those measured in vivo , including a low permeability, TEER values 10 times higher than in transwells, and an enhanced expression of pump molecules
It is a small-molecule enzyme inhibitor
But convenience means nothing if the dosing is wrong
10.1016/j.canlet.2017.05.010 237 RasinarA.-D.MoraruD.LazrR.PtruicS
This product is not intended for therapeutic, diagnostic, cosmetic, personal, or human use, and must be stored and handled according to institutional SOPs