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Mimo to przy aktywnej chorobie nowotworowej, podejrzeniu nowotworu, niewyjanionych zmianach guzowatych lub wieo zakoczonym leczeniu onkologicznym zachowabym ostrono

A cell in a dish does not know whether the peptide reached it from a cream or from the bloodstream

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doi:10.1016/j.cofs.2016.02.002 [Elsevier] 116

The primary molecular actions relevant to skin are: modulation of TGF- signaling (upregulating TGF-1 for collagen I/III synthesis while suppressing TGF-2 to prevent scarring), decorin upregulation for orderly collagen fibril assembly, MMP suppression paired with TIMP upregulation to preserve ECM integrity, and copper-dependent lysyl oxidase activation for collagen crosslinking