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Positioned as a potential physiological regulator, LR3 IGF-I may govern [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts, demonstrating effective stimulation of glucose transport in bone-derived osteoblastic (PyMS) cells even at markedly lower concentrations than insulin

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This increases fat deposition in the walls of the arteries, which drives atherosclerosis

Petit, N

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The oncogenic transcription factor c-Jun is reported to elevate the expression of mitochondrial glutaminase by directly binding to its promoter region in breast cancer cells [12]