(Native, unmodified recombinant human IGF-1, sold as mecasermin/Increlex, is FDA-approved only for a narrow pediatric growth-failure indication and is chemically distinct from the LR3 analog.) In the US it is manufactured and sold almost exclusively as an unregulated "research chemical" labeled "not for human consumption," a labeling practice peptide vendors use to avoid marketing it as an unapproved drug
Kwashiorkor (E40) : Predominant protein deficiency with relatively adequate caloric intake
10.14814/phy2.13182 Physiol Rep
Accessed January 14, 2025
Sun sensitivity increases significantly during treatment because newly exposed skin layers are more vulnerable to UV damage, requiring SPF 30+ sunscreen even on cloudy days
Frontiers in Aging Neuroscience, 11, 257