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Individuals diagnosed with pernicious anemia, a condition where the body cannot absorb B12 from the digestive tract, are prime candidates for these injections

Yoon S, Seger R (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

doi: 10.1016/j.ejogrb.2010.06.012 137

1 Introduction Berberine (C 20 H 18 NO 4 , IUPAC name: 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo [11.8.0.0 2,10 .0 4,8 .0 15,20 ] henicosa-1(13),2,4(8),9,14,16,18,20-octaene, PubChem CID: 2353), an isoquinoline quaternary alkaloid, isolated from different medicinal plants with a molar weight of 336.36 g/mol, including Hydrastis canadensis , Xanthorhiza simplicissima , Berberis aristata , Coptis chinensis , Coptis japonica , etc

3.3 Huntington's disease (HD) HD is caused by a mutation in the Huntingtin protein, which results in the aggregation of this protein in the neurons of HD patients (55)

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