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COVID-19 metabolism: mechanisms and therapeutic targets

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Specialized pro-resolving mediators (SPMs) are a class of PUFA-derived lipid mediators (49)

A simplified form of the reaction follows: Equation 2: X-Z + GS- GS-X + Z- Pumps that recognize the glutathione conjugated with a xenobiotic (Figure 21) (GS-X) have been described in animal plasmamembranes and plant tonoplast membranes

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Un factor que influye en el estado del glutatin es el grado de variabilidad en la capacidad de un individuo para producir glutatin, debido principalmente a la variabilidad gentica en las enzimas (glutatinn S-transferasa, la gamma-glutamil transferasa) implicadas en su produccin y/o regeneracin