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Furthermore, butyrate, which is one of the SCFAs, can inhibit NF-B activation, HDACs, and upregulate PPAR- [149], demonstrating anti-inflammatory and oxidative stress-modulating effects
Molecular basis of the KEAP1-NRF2 Signaling pathway
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When combined with insulin or sulfonylureas, dose adjustments of these medications are frequently necessary to reduce the risk of hypoglycemia, as the glucose-lowering effects may be additive
