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For instance, firstly, there should be initial treatment of motor PD

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Strassman AM, Melo-Carrillo A, Houle TT et al (2022) Atogepant an orally-administered CGRP antagonist attenuates activation of meningeal nociceptors by CSD

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The exothermicity of the interaction of the peptide during titration with collagen is very high, indicating the strong binding ability