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The mass transitions for the internal standard, acetaminophen and its metabolites were 136 94 (acetanilide, internal standard), 152 110 (acetaminophen), 457 328 (glutathione conjugate), 328 182 (cysteine conjugate), and 314 152 110 (glucoside conjugate)
It also causes nausea, headache, and allergy-like histamine release
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It is about optimizing conditions for maximum absorption while minimizing loss