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For those who have chronic hepatitis B without cirrhosis, screening should begin at age 20 years for African-born persons, 40 years for Asian-born men, and 50 years for Asian-born women, and for patients with a family history of HCC, high HBV DNA level, and a persistent or intermittent increase in the level of alanine aminotransferase

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Their efficacy has not been confirmed by FDA-approved research, and they are not intended to diagnose, treat, cure, or prevent any disease