The peptide exhibits high-affinity copper binding (Kd ~10 M), creating a stable complex that delivers copper to cells while protecting against copper-induced oxidative damage
doi:10.1002/cbf.937 Michelet F, Gueguen R, Leroy P, Wellman M, Nicolas A, Siest G (1995) Blood and plasma glutathione measured in healthy subjects by HPLC: relation to sex, aging, biological variables, and life habits
It is water soluble, scavenges free radicals and can even influence glutathione production
The peptide has shown effectiveness in treating skin burns and alleviating discomfort associated with gastrointestinal conditions such as Crohns disease, stomach ulcers, and cramps
Also See: For a comprehensive overview of GHK-Cu research, mechanisms, UK sourcing, and safety data, see our GHK-Cu Copper Peptide Research Guide
Furthermore, the endoplasmic reticulum releases calcium in response to EPAC2 activation, increasing intracellular calcium levels and promoting exocytosis
