A recent study reported that suppression of HMGB1 could alleviate high glucose-induced ferroptosis in glomerular mesangial cells and ameliorate the progression of inflammation
n a complementary manner, the demethylase KDM3B inhibits ferroptosis by removing H3K9 methylation marks, thereby enhancing SLC7A11 expression (210)
doi: 10.1093/nar/gkae973 Summary Keywords atheroscelrosis, cholesterol metabolism, acetyl-L-carnitine (ALC), SREBP2, HMGCR Citation Xing J, Du Z, Li F, Wang Y, Zhang Z, Gao X, Han L, Sun X, Sun H, Du Y, Hu C, Yu H and Qin Y (2024) Acetyl-L-carnitine ameliorates atherosclerosis in LDLR / mice by modulating cholesterol metabolism through SREBP2-dependent cholesterol biosynthesis
Redox biochemistry of mammalian metallothioneins
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The role of glutathione in cancer