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Low Se concentration may increase sperm susceptibility to free radicals, which may disturb the biochemical processes taking place in the acrosome [138]

531 Fer-1 inhibits iron accumulation, lipid peroxidation, thereby alleviating atherosclerotic damage in Apolipoprotein E -/- (ApoE -/- ) mice fed a high-fat diet

Antioxidant defense Promotes glutathione production to combat oxidative stress

HGSCs are characterized by xCT overexpression along with the activation of GSH biosynthesis [48]

For example, vessel branching by endothelial cells was shown to depend on an upregulation of glycolysis via phosphofructokinase-2/fructose-2,6-bisphosphatase 3 (PFKFB3), which synthesizes F2,6BP, an allosteric activator of PFK-1 and the most potent stimulator of glycolysis 75,78

However, scientists discovered that EPO also has powerful tissue-protective effects