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It can be described as a mild sedative in humans, primarily because micromolar concentrations of the flavonoids bind benzodiazepine receptors and consequently increase brain gamma-aminobutyric acid (GABA) concentrations, producing a sedative effect [127, 128] The anxiolytic effect of chamomile was experimentally demonstrated in one clinical trial, with significantly lowered scores in the Community Mental Health Modal Programmed in the chamomile group