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chronic diseases combined with other chronic diseases, such as congenital heart disease, congenital immunodeficiency, etc., there may be obvious congenital abnormalities that are related to the immune or respiratory system

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Aerobic exercise is associated with beneficial effects on brain health such that increased physical activity is associated with attenuated rate of age-related cortical atrophy (Colcombe et al., 2003), hippocampal growth (Erickson et al., 2011

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The regulation of diverse transcription factors, receptors for growth factors (including FGFR2b, FGFR2c, EGFR and HER2), and the activation of Akt are other elements in the reversion of MET [24]

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